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25T-NBOMe

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25T-NBOMe
Clinical data
Other names2C-T-NBOMe; NBOMe-2C-T; N-(2-Methoxybenzyl)-4-methylthio-2,5-dimethoxyphenethylamine
Drug classSerotonin 5-HT2 receptor agonist; Possible serotonergic psychedelic; Possible hallucinogen
ATC code
  • None
Identifiers
  • 2-(2,5-dimethoxy-4-methylsulfanylphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC19H25NO3S
Molar mass347.47 g·mol−1
3D model (JSmol)
  • COC1=CC=CC=C1CNCCC2=CC(=C(C=C2OC)SC)OC
  • InChI=1S/C19H25NO3S/c1-21-16-8-6-5-7-15(16)13-20-10-9-14-11-18(23-3)19(24-4)12-17(14)22-2/h5-8,11-12,20H,9-10,13H2,1-4H3
  • Key:ZWPIZVVOKGWMFW-UHFFFAOYSA-N

25T-NBOMe, also known as 2C-T-NBOMe or NBOMe-2C-T as well as N-(2-methoxybenzyl)-4-methylthio-2,5-dimethoxyphenethylamine, is a serotonin 5-HT2 receptor agonist and possible serotonergic psychedelic of the phenethylamine, 2C, and 25-NB (NBOMe) families.[1][2] It is the NBOMe (N-(2-methoxybenzyl)) derivative of 2C-T.[1][2] The drug acts as a potent agonist of the serotonin 5-HT2A and 5-HT2C receptors and also shows interactions with certain other targets, such as the serotonin 5-HT2B receptor.[1][2] It was first described in the scientific literature by 2010.[1]

See also

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References

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  1. ^ a b c d Hansen M (2010-12-16). Design and Synthesis of Selective Serotonin Receptor Agonists for Positron Emission Tomography Imaging of the Brain (Ph.D. thesis). University of Copenhagen. doi:10.13140/RG.2.2.33671.14245.
  2. ^ a b c Hansen M, Phonekeo K, Paine JS, Leth-Petersen S, Begtrup M, Bräuner-Osborne H, Kristensen JL (March 2014). "Synthesis and structure-activity relationships of N-benzyl phenethylamines as 5-HT2A/2C agonists". ACS Chemical Neuroscience. 5 (3): 243–249. doi:10.1021/cn400216u. PMC 3963123. PMID 24397362.
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