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Ergocornine

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Ergocornine
Identifiers
  • 12′-Hydroxy-2′,5′-α-bis(1-methyl-ethyl)ergotaman-3′,6′,18-trione
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.008.430 Edit this at Wikidata
Chemical and physical data
FormulaC31H39N5O5
Molar mass561.683 g·mol−1
3D model (JSmol)
  • O=C3N1CCC[C@H]1[C@]2(O)O[C@](C(=O)N2[C@H]3C(C)C)(NC(=O)[C@@H]7/C=C6/c4cccc5c4c(c[nH]5)C[C@H]6N(C)C7)C(C)C
  • InChI=1S/C31H39N5O5/c1-16(2)26-28(38)35-11-7-10-24(35)31(40)36(26)29(39)30(41-31,17(3)4)33-27(37)19-12-21-20-8-6-9-22-25(20)18(14-32-22)13-23(21)34(5)15-19/h6,8-9,12,14,16-17,19,23-24,26,32,40H,7,10-11,13,15H2,1-5H3,(H,33,37)/t19-,23-,24+,26+,30-,31+/m1/s1 ☒N
  • Key:UJYGDMFEEDNVBF-OGGGUQDZSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Ergocornine is a crystalline ergopeptine and one of the ergot alkaloids separated from ergotoxine. It is also a dopamine receptor agonist.[1] It was discovered by Albert Hofmann, the Swiss chemist who created LSD.[2]

References

[edit]
  1. ^ Fuxe K, Corrodi H, Hökfelt T, Lidbrink P, Ungerstedt U (April 1974). "Ergocornine and 2-Br-alpha-ergocryptine. Evidence for prolonged dopamine receptor stimulation". Medical Biology. 52 (2): 121–32. PMID 4837435.
  2. ^ Stoll A, Hoffmann A (1965). "Chapter 21: The Ergot Alkaloids". In Manske RH (ed.). Indole alkaloids. The alkaloids: chemistry and physiology. Vol. 8. New York: Academic Press. p. 759. ISBN 978-0-08-086532-4.


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