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Former featured articleDown syndrome is a former featured article. Please see the links under Article milestones below for its original nomination page (for older articles, check the nomination archive) and why it was removed.
Good articleDown syndrome has been listed as one of the Natural sciences good articles under the good article criteria. If you can improve it further, please do so. If it no longer meets these criteria, you can reassess it.
Main Page trophyThis article appeared on Wikipedia's Main Page as Today's featured article on December 5, 2006.
Article milestones
DateProcessResult
July 4, 2006Peer reviewReviewed
September 12, 2006Featured article candidatePromoted
November 1, 2010Featured article reviewDemoted
September 7, 2012Peer reviewReviewed
March 25, 2014Good article nomineeListed
Current status: Former featured article, current good article

usage error in the infobox

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it reads "life long". it should read "lifelong".

I'm literally replying here just to add my sig which will allow archiving to happen, now it's been fixed. For the record, the term "life long" no longer appears in the article anyway. Chaheel Riens (talk) 12:40, 6 June 2025 (UTC)[reply]

Male parents with Down Syndrome

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I don't get the part where it says there were three fathers with Down Syndrome as of 2006. There's three fathers with Down Syndrome on the entire planet? 2605:6DC0:E000:1BCB:4C66:E6D2:6EC9:51B6 (talk) 22:48, 31 March 2025 (UTC)[reply]

The reference cited was a case report that claimed 3 males with Down Syndrome fathered children. It made no claim about the planet, but rather that these cases are unusual. The sentence was confusing, I don't think it adds to the article and I deleted it. The same reference is used the previous, clearer sentence. Johnjbarton (talk) 23:34, 31 March 2025 (UTC)[reply]
okey dokey 2605:6DC0:E000:1BCB:4C66:E6D2:6EC9:51B6 (talk) 01:50, 1 April 2025 (UTC)[reply]

Kanako the chimpanzee

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An update on the chimp with Down syndrome: she died in 2020, aged 27. Article should be updated to reflect this. 71.195.26.4 (talk) 23:42, 23 May 2025 (UTC)[reply]

 Done Johnjbarton (talk) 02:36, 24 May 2025 (UTC)[reply]

Semi-protected edit request on 24 May 2025

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Wanted to include a diagram of nondisjunction during the meiosis I phase of the maternal cell for users to easily imagine it on the side of this text: "Down syndrome (also known by the karyotype 47,XX,+21 for females and 47,XY,+21 for males)[99] is mostly caused by a failure of the 21st chromosome to separate during egg or sperm development, known as nondisjunction.[92] As a result, a sperm or egg cell is produced with an extra copy of chromosome 21; this cell thus has 24 chromosomes. When combined with a normal cell from the other parent, the baby has 47 chromosomes, with three copies of chromosome 21.[3][92] About 88% of cases of trisomy 21 result from nonseparation of the chromosomes in the mother, 8% from nonseparation in the father, and 3% after the egg and sperm have merged.[100]". Just a simple image, nothing complex. My image that I have created can be found here: https://commons.wikimedia.org/wiki/File:Biology_Missing_Wikipedia_Project_(1).jpg Willnpp11 (talk) 05:05, 24 May 2025 (UTC)[reply]

Thanks. I have two suggestions.
First the file should be renamed. There are thousands of images in wikipedia and perhaps a million missing ones ;-). Something like Nondisjunction_in_trisomy-21 for example.
Second, I think the cell divisions are obvious but the last two lines of image may be confusing to some readers. Mother and father lines have 4 cells but only one of each shows up in the last line. Perhaps the joining action of the two cells lines could be labeled "Fertilization"? Johnjbarton (talk) 15:42, 24 May 2025 (UTC)[reply]

Spelling error

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"The mechanism is not inherited. tThere is no scientific research which shows that environmental factors or the parents' activities contribute to Down syndrome." Spelling mistake in the Cause section, the letter t is repeated, first in lowercase case, then in uppercase. Namek Trotu (talk) 05:46, 25 May 2025 (UTC)[reply]

Fixed - thanks for spotting. Chaheel Riens (talk) 08:25, 25 May 2025 (UTC)[reply]

Semi-protected edit request on 27 May 2025

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Please change "Two efforts being studied are the use stem cells..." to "Two efforts being studied are the use of stem cells..." (added "of" before stem cells) in the "Reasearch" section (grammatical error). Aspidthesnake (talk) 20:41, 27 May 2025 (UTC)[reply]

Well I got carried away and rewrote the section. Please review. Johnjbarton (talk) 23:01, 27 May 2025 (UTC)[reply]
In the rewritten section there are two new errors in the sentence "Gene therapy delivered via stem cells has proposed as a tool for studying the syndrome and and an approach to therapy.". The correct version would be "Gene therapy delivered via stem cells has been proposed as a tool for studying the syndrome and an approach to therapy." ( changed "has" to "has been" and removed duplicate "and") Aspidthesnake (talk) 08:53, 28 May 2025 (UTC)[reply]
 Done thanks Johnjbarton (talk) 15:00, 28 May 2025 (UTC)[reply]