Talk:A2 milk

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Update

I love a nice EFSA review as much as everyone else, but 2009 might be stretching it.

Regarding the issue of whether human digestion produces bBCM7, the Boutrou et al (2013) study cited by Brooke-Taylor et al. (2017) doi:10.3945/an.116.013953 looks promising enough. They use peptide sequencing to show that BCM7 really is there with none of the "immunoreactive" bull.
Regarding the issue of any direct disease link, nothing direct yet, at least going by the reference list of PMC 8345738, whose authors obviously want to find the strongest human proof for the BCM7-harmful theory.
Regarding GI discomfort, the PMC article from above does cite two Chinese ClinicalTrials.gov-registered RCTs comparing regular to A2 milk. They have been cited in one 2017 systematic review, PMID 28916574, which still admits that more human trials are needed. PMID 30722004 (2019), which uses more trials, is able to provide "moderate certainty for adverse digestive health effects". There are newer, unreviewed RCTs being continuously done, with two recent ones being PMID 38957588 and PMID 40338897.

Artoria 2e5 🌉 06:28, 18 May 2025 (UTC)[reply]