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Mark Andrew Estelle

From Wikipedia, the free encyclopedia

Mark Andrew Estelle is a Canadian-American biologist known for his work elucidating the mechanism of the plant hormone, auxin using the model plant Arabidopsis thaliana. He is currently a Distinguished Professor at University of California San Diego.

Life and career

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Early life

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Mark Andrew Estelle was born in Calgary Alberta, Canada in 1955.[citation needed] His undergraduate and graduate education emphasized genetic approaches to problems, regardless of species or organism which helped him develop a broad view of approaching scientific investigation (https://aspb.org/wp-content/uploads/2023/01/ASPBPioneerMember_Mark-Estelle.pdf).[citation needed]

Education

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Mark earned his BS. degree at University of Alberta B.S. in 1978.[1] He earned his Ph.D. in genetics from the University of Alberta in 1983.[1] His doctoral research involved the fruit fly and was entitled "The analysis of a dopa decarboxylase activity variant in Drosophila melanogaster" (https://era.library.ualberta.ca/search?search=mark+A+estelle)[citation needed]

Mark Estelle continued his scientific training as a research associate of the Michigan State University-U.S. Department of Energy Plant Research Laboratory with Dr. Chris R. Somerville (1983-86).[1][2]

In 1986, he was hired as an Assistant Professor at Indiana University and eventually became the Indiana University Miller Chair in Plant Developmental Biology 2002-2008.[3][4] He later moved his research lab to the University of California San Diego as a Distinguished Professor, Department of Cellular and Developmental Biology 2008-present.[5]

Research areas

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Estelle's laboratory utilizes the plant Arabidopsis thaliana to identify auxin response pathways. His group determined that auxin response depends on the degradation of transcriptional repressors called the Aux/IAA proteins with requires the ubiquitin protein ligase E3 called SCFTIR1.[6]

Recognition

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See also

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References

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  1. ^ a b c "Mark Estelle: University Honors and Awards: Indiana University". University Honors & Awards. Retrieved 2025-06-02.
  2. ^ "Plant Biology Tree - Mark Estelle". academictree.org. Retrieved 2025-06-02.
  3. ^ "Mark Estelle: University Honors and Awards: Indiana University". University Honors & Awards. Retrieved 2025-06-02.
  4. ^ "Mark Estelle: IU Alliance: Indiana University". IU Alliance of Distinguished and Titled Professors. Retrieved 2025-06-04.
  5. ^ "Mark Estelle".
  6. ^ a b "Mark Estelle – NAS". www.nasonline.org/. Retrieved 2025-06-02.
  7. ^ "Mark Estelle, PhD | Former Investigator Profile | 2011-2018". www.hhmi.org. Retrieved 2025-06-02.
  8. ^ "Grant Detail". www.moore.org. Retrieved 2025-06-04.
  9. ^ "Historic Fellows | American Association for the Advancement of Science (AAAS)". www.aaas.org. Retrieved 2025-06-02.
  10. ^ "Member Directory - NAS". www.nasonline.org/. Retrieved 2025-06-02.
  11. ^ "Pioneers Mark Estelle". American Society of Plant Biologists. Retrieved 2025-06-02.
  12. ^ "Anton Lang Award". prl.natsci.msu.edu. Retrieved 2025-06-04.
  13. ^ "The Woolhouse Lecture". John Innes Centre. Retrieved 2025-06-04.