Edison Liu
Edison Tak-Bun Liu is an American chemist and former president and CEO of The Jackson Laboratory and director of its NCI-designated Cancer Center (2012–2021). He previously served as founding executive director of the Genome Institute of Singapore (GIS), chairman of the Health Sciences Authority, and president of the Human Genome Organization (HUGO) (2007–2013).[1][2]
From 1997 to 2001, he was scientific director of the National Cancer Institute's Division of Clinical Sciences. At the University of North Carolina at Chapel Hill (1987–1996), he held leadership roles at the Lineberger Comprehensive Cancer Center, UNC School of Public Health, and CALGB.[3][4]
Education
[edit]Edison T. Liu earned his B.S. in Chemistry and Psychology from Stanford University in 1973, followed by an M.D. from the Stanford University School of Medicine in 1978. He completed his internship (1978–1979) and residency (1979–1980) at Barnes Hospital, affiliated with Washington University in St. Louis. Liu then pursued an oncology fellowship at Stanford University (1980–1982) and a hematology fellowship at University of California San Francisco, Moffitt Hospital (1982–1985).[5] From 1983 to 1987, he was a postdoctoral fellow in the Department of Microbiology at the University of California at San Francisco, working in the laboratory of Dr. J. Michael Bishop.[6]
Professional appointments
[edit]Liu has served as Professor, President Emeritus, and Honorary Fellow at The Jackson Laboratory, where he was previously President and CEO from 2011 to 2021. From 2001 to 2011, he was Executive Director of the Genome Institute of Singapore, and concurrently served as Chairman of the Governing Board of the Health Sciences Authority of Singapore (2007–2011). Prior to that, Liu was Director of the Division of Clinical Sciences at the National Cancer Institute (1996–2001).[7]
At the University of North Carolina at Chapel Hill, he held several academic and leadership roles, including Chief of the Division of Medical Genetics and Professor in the Departments of Medicine, Epidemiology, Biochemistry, and Biophysics (1995–1996), Associate Professor (1993–1995), and Assistant Professor in Medicine and Oncology (1987–1993). He also directed the NIH-designated Specialized Program of Research Excellence in Breast Cancer from 1992 to 1996.[8]
Research
[edit]Liu's scientific research has focused on the functional genomics of human cancers, particularly breast cancer (identifying the tandem duplicator phenotype genomic configuration[9]), discovering new oncogenes (AXL family of receptor tyrosine kinases[10]), and deciphering the dynamics of gene regulation on a genomic scale that modulates cancer biology.[11] His work has spanned basic to population sciences to translation to the clinic. He has authored over 320 scientific papers and reviews, and co-authored two books.
In his spare time, Liu[12] pursues jazz piano and composition, and writes for the lay public on science, medicine and society.
Honors and awards
[edit]- 2018 Honorary Degree recipient, University of Southern Maine
- 2016 Honorary Degree recipient, Colby College[13]
- 2016 Elected Fellow, American Association for the Advancement of Science
- 2014 Chen Award for Distinguished Academic Achievement in Human Genetic and Genomic Research (from Human Genome Organization)
- 2010 Fellow, The Hastings Center
- 2008 Associate (Foreign) Member European Molecular Biology Organization (EMBO)
- 2007-2013 President, the Human Genome Organization (HUGO)
- 2007 Doctor of Medical Science honoris causa, awarded by Queen's University Belfast
- 2005 National Healthcare Group (NHG), Singapore, Distinguished Contributor Award
- 2003 Public Service Medal (National Day, 2003), for work in controlling SARS in Singapore (given by the Office of the President, Republic of Singapore)
- 2000 Rosenthal Award, AACR: for the discovery that HER-2 status determines response to adjuvant chemotherapy with doxorubicin
- 1999 Elected-Board of Directors, American Association for Cancer Research
- 1996 Brinker International Award for Breast Cancer Research - Basic Research Award
- 1995 American Society of Clinical Investigation (Membership)
- 1991-1996 Leukemia and Lymphoma Society Scholar
- 1985-1988 Clinical Investigator Award, National Cancer Institute, K08-CA01036-02, Preceptor: Dr. J. Michael Bishop.
- 1983-1985 Damon Runyan Cancer Fund Fellowship Preceptor: Dr. J. Michael Bishop (UCSF)
- 1973 Phi Beta Kappa
References
[edit]- ^ Hutchinson, Ezzie (1 June 2001). "Edison Liu — Director of the Genome Institute of Singapore". The Lancet Oncology. pp. 385–388. doi:10.1016/S1470-2045(00)00394-6.
- ^ "Edison T. Liu". The Medicine Maker.
- ^ "Watch: Like a Boss Now: One-on-one with Dr. Edison Liu, President and CEO of The Jackson Laboratory". Press Herald. 4 May 2020.
- ^ Kevin, Brian (18 April 2019). "Dr. Edison Liu's Favorite Place". Down East Magazine.
- ^ Stevens, Shelby. "The Future of Genomics and Breast Cancer According to Dr. Edison T. Liu". The Colgate Maroon-News.
- ^ "Jackson Laboratory's Edison Liu Is Keynote at 40th Annual Meeting of the Academy". Connecticut Academy of Science and Engineering. 11 May 2015.
- ^ "Dr. Edison Liu". The Maine Mag. 14 January 2014.
- ^ "Edison T. Liu of The Jackson Laboratory named 2016 AAAS Fellow". EurekAlert!.
- ^ Menghi, Francesca; Barthel, Floris P.; Yadav, Vinod; Tang, Ming; Ji, Bo; Tang, Zhonghui; Carter, Gregory W.; Ruan, Yijun; Scully, Ralph; Verhaak, Roel G.W.; Jonkers, Jos; Liu, Edison (2018). "The Tandem Duplicator Phenotype Is a Prevalent Genome-Wide Cancer Configuration Driven by Distinct Gene Mutations". Cancer Cell. 34 (2): 197–210.e5. doi:10.1016/j.ccell.2018.06.008. PMC 6481635. PMID 30017478.
- ^ O'Bryan, J. P.; Frye, R. A.; Cogswell, P. C.; Neubauer, A.; Kitch, B.; Prokop, C.; R Espinosa, 3rd; Beau, M. M. Le; Earp, H. S.; Liu, E. T. (1991). "axl, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase". Molecular and Cellular Biology. 11 (10): 5016–5031. doi:10.1128/mcb.11.10.5016-5031.1991. PMC 361494. PMID 1656220. S2CID 44190723.
{{cite journal}}: CS1 maint: numeric names: authors list (link) - ^ Fullwood, Melissa J.; Liu, Mei Hui; Pan, You Fu; Liu, Jun; Xu, Han; Mohamed, Yusoff Bin; Orlov, Yuriy L.; Velkov, Stoyan; Ho, Andrea; Mei, Poh Huay; Chew, Elaine G. Y. (2009). "An oestrogen-receptor-α-bound human chromatin interactome". Nature. 462 (7269): 58–64. Bibcode:2009Natur.462...58F. doi:10.1038/nature08497. ISSN 0028-0836. PMC 2774924. PMID 19890323.
- ^ "Leading up".
- ^ "Honorary Degree Citations". Commencement. 2016-05-22. Retrieved 2016-06-10.
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