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Draft:Lieselotte Obst-Huebl

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Lieselotte Obst-Huebl is a German research scientist at the Berkeley Lab Laser Accelerator (BELLA) Center[1], where she leads high energy density science experiments and supports user campaigns at the BELLA petawatt (PW) laser system.[2] Her research encompasses laser-driven ion acceleration (a technique to generate high-energy ions using intense laser pulses), plasma mirror development (creating reflective surfaces from ionized gas to improve laser focus and contrast), targetry (the design and preparation of targets for laser experiments), and diagnostics (methods for monitoring and analyzing experimental conditions and outcomes)

Education

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Obst-Huebl earned her Diplom (equivalent to a master's degree) in physics from Technische Universität Dresden in 2014. She completed her Ph.D. in physics at the same institution in 2019, conducting her doctoral research at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR). Her dissertation work received the Outstanding Doctoral Thesis Award from the American Physical Society (APS).[3]

Research

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At the BELLA Center, Obst-Huebl leads high energy density science experiments utilizing the BELLA Petawatt (PW) laser system. Her research encompasses laser-driven ion acceleration, plasma mirror development, targetry, and diagnostics.

She has contributed to the development of compact, tunable proton beamlines for ultra-high dose rate radiobiological studies, including investigations into the FLASH effect in cancer therapy.[4]

Selected Publications:

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  1. Bin, J., Obst-Huebl, L., Mao, J.-H., et al. (2022). "A new platform for ultra-high dose rate radiobiological research using the BELLA PW laser proton beamline." Scientific Reports, 12, 1585.[5]
  2. Obst-Huebl, L., Ziegler, T., Brack, F.-E., et al. (2018). "All-optical structuring of laser-driven proton beam profiles." Nature Communications, 9, 5292.[6]
  3. De Chant, J., Obst-Huebl, L., Nakamura, K., et al. (2022). "Modeling and design of compact, permanent-magnet transport systems for highly divergent, broad energy spread laser-driven proton beams" Phys.Rev.Accel.Beams 28, 033501.[7]

Research Impact or Relevance

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Her work supports advancements in both fundamental physics and applied medical research. In particular, the development of laser-based proton beams has potential uses in proton therapy for cancer, offering precise and potentially less damaging treatment alternatives to conventional radiation therapy.

References

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  1. ^ "Berkeley Lab Laser Accelerator (BELLA) Center – Accelerator Technology & Applied Physics Division". atap.lbl.gov. Retrieved 2025-04-17.
  2. ^ "Lieselotte Obst-Huebl | LaserNetUS". lasernetus.org. Retrieved 2025-03-25.
  3. ^ "Discovery". profiles.lbl.gov. Retrieved 2025-03-25.
  4. ^ Bin, Jianhui; Obst-Huebl, Lieselotte; Mao, Jian-Hua; Nakamura, Kei; Geulig, Laura D.; Chang, Hang; Ji, Qing; He, Li; De Chant, Jared; Kober, Zachary; Gonsalves, Anthony J.; Bulanov, Stepan; Celniker, Susan E.; Schroeder, Carl B.; Geddes, Cameron G. R. (2022-01-27). "A new platform for ultra-high dose rate radiobiological research using the BELLA PW laser proton beamline". Scientific Reports. 12 (1): 1484. Bibcode:2022NatSR..12.1484B. doi:10.1038/s41598-022-05181-3. ISSN 2045-2322. PMC 8795353. PMID 35087083.
  5. ^ Bin, Jianhui; Obst-Huebl, Lieselotte; Mao, Jian-Hua; Nakamura, Kei; Geulig, Laura D.; Chang, Hang; Ji, Qing; He, Li; De Chant, Jared; Kober, Zachary; Gonsalves, Anthony J.; Bulanov, Stepan; Celniker, Susan E.; Schroeder, Carl B.; Geddes, Cameron G. R. (2022-01-27). "A new platform for ultra-high dose rate radiobiological research using the BELLA PW laser proton beamline". Scientific Reports. 12 (1): 1484. Bibcode:2022NatSR..12.1484B. doi:10.1038/s41598-022-05181-3. ISSN 2045-2322. PMC 8795353. PMID 35087083.
  6. ^ Obst-Huebl, Lieselotte; Ziegler, Tim; Brack, Florian-Emanuel; Branco, João; Bussmann, Michael; Cowan, Thomas E.; Curry, Chandra B.; Fiuza, Frederico; Garten, Marco; Gauthier, Maxence; Göde, Sebastian; Glenzer, Siegfried H.; Huebl, Axel; Irman, Arie; Kim, Jongjin B. (2018-12-13). "All-optical structuring of laser-driven proton beam profiles". Nature Communications. 9 (1): 5292. Bibcode:2018NatCo...9.5292O. doi:10.1038/s41467-018-07756-z. ISSN 2041-1723. PMC 6294339. PMID 30546015.
  7. ^ De Chant, J.; Nakamura, K.; Ji, Q.; Obst-Huebl, L.; Barber, S.; Snijders, A. M.; Geddes, C. G. R.; van Tilborg, J.; Gonsalves, A. J.; Schroeder, C. B.; Esarey, E. (2025-03-13). "Modeling and design of compact, permanent-magnet transport systems for highly divergent, broad energy spread laser-driven proton beams". Physical Review Accelerators and Beams. 28 (3): 033501. arXiv:2411.03543. Bibcode:2025PhRvS..28c3501D. doi:10.1103/PhysRevAccelBeams.28.033501.