Atelectotrauma

In medicine, atelectotrauma, atelectrauma, cyclic atelectasis or repeated alveolar collapse and expansion (RACE) is the damage caused to the lung by mechanical ventilation under certain conditions.
Disorder
[edit]When parts of the lung collapse at the end of expiration, due to a combination of a diseased lung state and a low functional residual capacity, then reopen again on inspiration, this repeated collapsing and reopening causes shear stress which has a damaging effect on the alveolus.[1][2] Clinicians attempt to reduce atelectotrauma by ensuring adequate positive end-expiratory pressure (PEEP) to maintain the alveoli open in expiration. This is known as open lung ventilation. High-frequency oscillatory ventilation (HFOV) with its use of super continuous positive airway pressure (CPAP) is especially effective in preventing atelectotrauma since it maintains a very high mean airway pressure (MAP), equivalent to a very high PEEP. Atelectotrauma is one of several means by which mechanical ventilation may damage the lungs leading to ventilator-associated lung injury. The other means are volutrauma, barotrauma, rheotrauma and biotrauma. Attempts have been made to combine these factors in an all encompassing term: mechanical power.
References
[edit]- ^ Shi C., Boehme S., Hartmann E. K., Markstaller K. Novel technologies to detect atelectotrauma in the injured lung. Exp Lung Res. 2011 Feb;37(1):18-25. PMID 20860539 [1]
- ^ Attar MA, Donn SM. Mechanisms of ventilator-induced lung injury in premature infants. Semin Neonatol. 2002 Oct;7(5):353-60. PMID 12464497 [2]