He founded Enne Limited in 2014 and is also founder and CEO of FIT Strategy. Since 2020,[4] Letteriello has been a member of the Massachusetts Institute of Technology's CDO Symposium Programme Committee and in 2021 was nominated High Level Facilitator Tracker for policy on building confidence and security in the use of ICTs. Holder of a Data Management Excellence Award, in 2021, Letteriello was nominated as one of the DataIq 100 most influential people in data.[5] He has also written for the World Economic Forum.[6] A resident of Modena, he lectures in Economics at the University of Modena,[7] and lives with his wife Renata and their two children.