Acetatifactor aquisgranensis
| Acetatifactor aquisgranensis | |
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| Species: | A. aquisgranensis
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| Binomial name | |
| Acetatifactor aquisgranensis | |
| Type strain | |
| CLA-AA-M01T (= DSM 110981T) | |
Acetatifactor aquisgranensis is a species of Gram-positive, obligately anaerobic bacteria belonging to the genus Acetatifactor. It was isolated from the cecal contents of a specific-pathogen-free laboratory mouse and described as a novel species in 2023.[1]
Etymology
[edit]The species name aquisgranensis is derived from the Latin name for Aachen, Germany (Aquisgranum), the location where the bacterium was first isolated.
Taxonomy
[edit]Based on 16S rRNA gene sequence similarity, A. aquisgranensis is most closely related to Acetatifactor muris, sharing 89.17% identity. Although this is below typical thresholds for species within the same genus, genome-based phylogeny and a percentage of conserved proteins (POCP) value of 59.45% support its inclusion in the genus Acetatifactor. Average nucleotide identity (ANI) between A. aquisgranensis and A. muris is 81.00%, and digital DNA–DNA hybridization (dDDH) is 29.10%, supporting its classification as a distinct species.
The strain was part of an expanded effort to culture members of the mouse gut microbiota, facilitating the design of custom synthetic communities for microbiome research.[2]
Morphology and physiology
[edit]Cells of A. aquisgranensis are straight to slightly curved rods, approximately 1–2 μm in length when grown anaerobically in brain heart infusion (BHI) medium for 3–7 days. Colonies grow under strictly anaerobic conditions. It produces acetate as the main fermentation product, with minor amounts of formate and butyrate also detected.[2]
See also
[edit]References
[edit]- ^ "Species: Acetatifactor aquisgranensis". List of Prokaryotic names with Standing in Nomenclature (LPSN). Retrieved 22 July 2025.
- ^ a b Afrizal, A; Jennings, SAV; Hitch, TCA; Riedel, T; Basic, M; Panyot, A; Treichel, N; Hager, FT; Wong, EO; Wolter, B; Viehof, A; von Strempel, A; Eberl, C; Buhl, EM; Abt, B; Bleich, A; Tolba, R; Blank, LM; Navarre, WW; Kiessling, F; Horz, HP; Torow, N; Cerovic, V; Stecher, B; Strowig, T; Overmann, J; Clavel, T (November 2022). "Enhanced cultured diversity of the mouse gut microbiota enables custom-made synthetic communities". Cell Host & Microbe. 30 (11): 1630–1645.e25. doi:10.1016/j.chom.2022.09.011. PMID 36208631.