Ruthenibacterium
| Ruthenibacterium | |
|---|---|
| Scientific classification | |
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| Genus: | Ruthenibacterium Shkoporov et al., 2016
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| Species: | R. lactatiformans
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| Binomial name | |
| Ruthenibacterium lactatiformans Shkoporov et al., 2016
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| Type strain | |
| DSM 100348, VKM B-2901, 585-1T | |
Ruthenibacterium is a genus of Gram-negative, obligately anaerobic, non-spore-forming bacteria within the family Oscillospiraceae. The genus was first described in 2016 with the identification of its type species, Ruthenibacterium lactatiformans, isolated from human feces.[1]
Taxonomy
[edit]The genus Ruthenibacterium was established by Shkoporov et al. in 2016 following the isolation and characterization of two novel strains (585-1T and 668) from the feces of healthy human subjects. Phylogenetic analysis based on 16S rRNA gene sequences indicated that these strains formed a distinct lineage within the family Oscillospiraceae, with less than 92% sequence similarity to their closest relatives, including Anaerofilum pentosovorans and Gemmiger formicilis.[1]
Species
[edit]Currently, the genus comprises a single validly published species:
Morphology and physiology
[edit]Ruthenibacterium lactatiformans is characterized as:
- Gram-negative in staining (despite phylogenetic placement among Gram-positive phyla)
- Rod-shaped and non-motile
- Non-spore-forming
- Strictly anaerobic
Ecology and clinical significance
[edit]Ruthenibacterium lactatiformans was originally isolated from the feces of healthy adult humans and is considered a commensal member of the gut microbiota. In 2024, the bacterium was identified in the first documented case of human infection. An elderly man with diabetes and renal failure developed vertebral osteomyelitis, and blood cultures later revealed the presence of R. lactatiformans using 16S rRNA gene sequencing.[2]
Type strain
[edit]The type strain is 585-1T, also known as:
- DSM 100348T
- VKM B-2901T
References
[edit]- ^ a b Shkoporov, Andrei N.; Chaplin, Andrei V.; Shcherbakova, Victoria A.; Suzina, Natalia E.; Kafarskaia, Lyudmila I.; Bozhenko, Vladimir K.; Efimov, Boris A. (August 2016). "Ruthenibacterium lactatiformans gen. nov., sp. nov., an anaerobic, lactate-producing member of the family Ruminococcaceae isolated from human faeces". International Journal of Systematic and Evolutionary Microbiology. 66 (8): 3041–3049. doi:10.1099/ijsem.0.001143. PMID 27242263.
- ^ Sumiyoshi, Shougen; Hamaguchi, Shigeto; Kimura, Keigo; Negishi, Katsuyuki; Ninomiya, Koshi; Sasaki, Manabu; Kutsuna, Satoshi (July 2024). "Ruthenibacterium lactatiformans isolated from a human blood culture: a first report". BMC Infectious Diseases. 24 (1): 699. doi:10.1186/s12879-024-09606-4. PMC 11247725. PMID 39009969.