EPN

EPN may refer to:

• End Polio Now, the Polio eradication campaign of Rotary International and the World Health Organization
• Economic Prosperity Network, a global alliance initiative of the first Trump administration
• EPN (insecticide)
• Effective perceived noise, a measure of aircraft noise
• Electronic Payments Network, an electronic clearing house
• Enrique Peña Nieto, President of Mexico 2012–2018
• Enterprise private network, an intranet in a large organisation
• Entomopathogenic nematode, thread worm that kills insects
• Epsin, a membrane protein
• Esplanade MRT station, Singapore (MRT station abbreviation)
• EUREF Permanent Network, a European GPS network
• National Polytechnic School (Ecuador) (Spanish: Escuela Politécnica Nacional), a university in Quito