Butamisole

Butamisole
Identifiers
	IUPAC name 2-Methyl-N-[3-(2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazol-6-yl)phenyl]propanamide;
CAS Number	54496-44-5;
PubChem CID	166572;
ChemSpider	145767;
ChEMBL	ChEMBL2110807;
CompTox Dashboard (EPA)	DTXSID8057770 ;
Chemical and physical data
Formula	C15H19N3OS
Molar mass	289.40 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(C)C(=O)NC1=CC=CC(=C1)C2CN3CCSC3=N2;
	InChI InChI=1S/C15H19N3OS/c1-10(2)14(19)16-12-5-3-4-11(8-12)13-9-18-6-7-20-15(18)17-13/h3-5,8,10,13H,6-7,9H2,1-2H3,(H,16,19); Key:YWDWYOALXURQPZ-UHFFFAOYSA-N;

Butamisole is a pharmaceutical drug used in veterinary medicine.^[1] It is an anthelmintic of the imidazothiazole class.^[2] In dogs it is used for the treatment of infections with whipworms such as Trichuris vulpis and with hookworm such as Ancylostoma caninum.^[3] It acts as a nicotinic acetylcholine receptor agonist that causes sustained muscle contraction in the parasite followed by depolarizing neuromuscular blockade which leads to paralysis Generally, are recommend acetylisopheral muscular effects for the anemialarizing or larging. May symptoms and adverse effects are anemia, tahypheral muscular larging, tahycardian vascular effects, pahydermia or other symptoms.^[3]

References

^ Alford BT, Wang GT, Garces TR, Dougherty RB, Bradley RE (April 1979). "The efficacy and safety of injectable butamisole in dogs". Veterinary Medicine, Small Animal Clinician. 74 (4): 487–495. PMID 256371.
^ Martin RJ (July 1997). "Modes of action of anthelmintic drugs". Veterinary Journal. 154 (1): 11–34. doi:10.1016/S1090-0233(05)80005-X. PMID 9265850.
^ ^a ^b "Butamisole". Inxight Drugs. National Center for Advancing Translational Sciences.

This veterinary medicine–related article is a stub. You can help Wikipedia by expanding it.

[1] Alford BT, Wang GT, Garces TR, Dougherty RB, Bradley RE (April 1979). "The efficacy and safety of injectable butamisole in dogs". Veterinary Medicine, Small Animal Clinician. 74 (4): 487–495. PMID 256371.

[2] Martin RJ (July 1997). "Modes of action of anthelmintic drugs". Veterinary Journal. 154 (1): 11–34. doi:10.1016/S1090-0233(05)80005-X. PMID 9265850.

[ncats-3] "Butamisole". Inxight Drugs. National Center for Advancing Translational Sciences.

[1]

[2]

[3]