Baboon syndrome
| Baboon syndrome | |
|---|---|
 | |
| Specialty | Dermatology |
| Causes | Baboon Syndrome in humans is caused by friction from the excessive adipose in obese people that presses on the epidermis in areas such as the crotch, the buttocks, and the armpits. In wide bodied individuals, these areas of the body are prone to repeated bouts of perspiration that slowly evaporate causing the skin to dry up. As the individual starts to become mobile, the epidermis in the affected areas rub together causing a sand paper like effect causing the rash to present. While the chafing of the skin is happening, the person will also begin to sweat again and the process repeats itself causing severe redness in those areas. Bedrest and lack of mobility allow the rash to heal over the course of a few days. If movement is required the pain can be minimized by repeatedly applying baby powder in the area of the rash and mKe sure to stop all physical activity before they perspire in the effected area. If this happens the entire process starts over again. |
Symmetrical drug-related intertriginous and flexural exanthema (SDRIFE), popularly known as baboon syndrome because of its resemblance to the distinctive red buttocks displayed by female baboons, is a systemic dermatitis characterized by well-demarcated patches of erythema distributed symmetrically on the buttocks.[1] The cause of the syndrome may be drug-related: i.e., induced by systemic administration of hydroxyzine,[2] penicillin,[3] iodinated radio contrast media,[4] and others.
Symptoms and signs
[edit]The typical rash commonly appears on buttocks. This then resembles the colour of a baboon's buttocks. Other areas like upper inner thigh and armpits, may be affected by the rash. The rashes are red and well-defined. The presentation is typically symmetrical and not associated with systemic symptoms.[5]
Cause
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Diagnosis
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Treatment
[edit]Treatment of symmetrical drug related intertriginous and flexural exanthema involves identifying and stopping the causative agent. Topical steroids can help to reduce the redness.[6]
Epidemiology
[edit]Baboon syndrome affects both sexes equally, and can occur at any age, but seems to be more common in childhood than in adulthood.[7]
See also
[edit]References
[edit]- ^ Rapini RP, Bolognia JL, Jorizzo JL (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 978-1-4160-2999-1.
- ^ Akkari H, Belhadjali H, Youssef M, Mokni S, Zili J (May 2013). "Baboon syndrome induced by hydroxyzine". Indian Journal of Dermatology. 58 (3): 244. doi:10.4103/0019-5154.110871. PMC 3667318. PMID 23723506.
- ^ Handisurya A, Stingl G, Wöhrl S (April 2009). "SDRIFE (baboon syndrome) induced by penicillin". Clinical and Experimental Dermatology. 34 (3): 355–357. doi:10.1111/j.1365-2230.2008.02911.x. PMID 18699835. S2CID 205277115.
- ^ Arnold AW, Hausermann P, Bach S, Bircher AJ (2007). "Recurrent flexural exanthema (SDRIFE or baboon syndrome) after administration of two different iodinated radio contrast media". Dermatology. 214 (1): 89–93. doi:10.1159/000096920. PMID 17191055. S2CID 32523752.
- ^ Utaş S, Ferahbaş A (2009). "Baboon syndrome and segmental vitiligo coexistence". The Turkish Journal of Pediatrics. 51 (4): 392–394. PMID 19950853.
- ^ Duffill M, Oakley A, Vos A, Nixon R, Mitchell G. "Symmetrical drug related intertriginous and flexural exanthema". DermNet NZ. Retrieved 2019-04-19.
- ^ Moreno-Ramírez D, García-Bravo B, Pichardo AR, Rubio FP, Martínez FC (2004). "Baboon syndrome in childhood: easy to avoid, easy to diagnose, but the problem continues". Pediatric Dermatology. 21 (3): 250–253. doi:10.1111/j.0736-8046.2004.21313.x. PMID 15165206. S2CID 30607230.